12 Spicy Southwest Style Meatloaf Recipes

Are you ready to turn up the heat in your kitchen with some bold, flavorful dishes? Our roundup of 12 Spicy Southwest Style Meatloaf Recipes is here to shake up your dinner routine. Perfect for home cooks looking to add a little kick to their comfort food, these recipes blend traditional meatloaf with vibrant Southwest flavors. Keep reading to discover your next favorite meal that’s sure to spice things up!

Southwest Chipotle Meatloaf

Back to basics with a twist, this Southwest Chipotle Meatloaf combines the comforting familiarity of a classic meatloaf with the bold flavors of the Southwest. Perfect for a weeknight dinner that feels anything but ordinary, let’s walk through the steps to create this flavorful dish.

Ingredients

• 1.5 lbs ground beef
• 1 cup breadcrumbs
• 1 large egg
• 1/2 cup milk
• 1/4 cup chipotle peppers in adobo sauce, finely chopped
• 1/2 cup onion, finely diced
• 1 tsp garlic powder
• 1 tsp cumin
• 1/2 tsp salt
• 1/4 cup ketchup
• 2 tbsp brown sugar
• 1 tbsp apple cider vinegar

Instructions

1. Preheat your oven to 375°F (190°C) and lightly grease a 9×5 inch loaf pan.
2. In a large mixing bowl, combine 1.5 lbs ground beef, 1 cup breadcrumbs, 1 large egg, 1/2 cup milk, 1/4 cup chipotle peppers, 1/2 cup onion, 1 tsp garlic powder, 1 tsp cumin, and 1/2 tsp salt. Mix until just combined; overmixing can make the meatloaf tough.
3. Transfer the mixture to the prepared loaf pan, pressing down gently to eliminate any air pockets.
4. In a small bowl, whisk together 1/4 cup ketchup, 2 tbsp brown sugar, and 1 tbsp apple cider vinegar. Spread this glaze evenly over the top of the meatloaf.
5. Bake in the preheated oven for 1 hour, or until the internal temperature reaches 160°F (71°C) when checked with a meat thermometer.
6. Let the meatloaf rest for 10 minutes before slicing to allow the juices to redistribute.

Juicy and packed with smoky, spicy flavors, this Southwest Chipotle Meatloaf is a surefire way to spice up your dinner routine. Serve it with a side of mashed sweet potatoes or a crisp green salad for a complete meal that’s bursting with flavor.

Spicy Jalapeno and Cheese Stuffed Meatloaf

Ready to elevate your meatloaf game with a spicy twist? This Spicy Jalapeno and Cheese Stuffed Meatloaf combines the comforting familiarity of classic meatloaf with the bold flavors of jalapeno and melted cheese, making it a perfect dish for those who love a little heat.

Ingredients

• 1.5 lbs ground beef
• 1 cup breadcrumbs
• 1 large egg
• 1/2 cup milk
• 1 tbsp Worcestershire sauce
• 1 tsp salt
• 1/2 tsp black pepper
• 2 jalapenos, finely diced
• 1 cup shredded cheddar cheese
• 1/2 cup ketchup
• 1 tbsp brown sugar
• 1 tsp mustard

Instructions

1. Preheat your oven to 375°F (190°C) and lightly grease a loaf pan.
2. In a large bowl, combine 1.5 lbs ground beef, 1 cup breadcrumbs, 1 large egg, 1/2 cup milk, 1 tbsp Worcestershire sauce, 1 tsp salt, and 1/2 tsp black pepper. Mix until just combined to avoid a tough meatloaf.
3. Divide the mixture in half. Press one half into the bottom of the prepared loaf pan.
4. Sprinkle 2 finely diced jalapenos and 1 cup shredded cheddar cheese evenly over the meat layer.
5. Top with the remaining meat mixture, sealing the edges to encase the filling.
6. In a small bowl, mix 1/2 cup ketchup, 1 tbsp brown sugar, and 1 tsp mustard. Spread this glaze over the top of the meatloaf.
7. Bake for 1 hour, or until the internal temperature reaches 160°F (71°C). Let it rest for 10 minutes before slicing to allow the juices to redistribute.

Yield a meatloaf that’s juicy on the inside with a slightly crispy, sweet glaze on the outside. The spicy jalapeno and gooey cheese filling make every bite exciting. Serve it with a side of mashed potatoes or a crisp salad for a complete meal.

BBQ Southwest Meatloaf with a Kick

Kickstart your culinary adventure with this BBQ Southwest Meatloaf with a Kick, a dish that combines the comforting familiarity of meatloaf with the bold flavors of the Southwest. Perfect for beginners, this recipe guides you through each step to ensure a delicious outcome.

Ingredients

• 1.5 lbs ground beef
• 1 cup breadcrumbs
• 1/2 cup BBQ sauce
• 1/4 cup milk
• 1 large egg
• 1 tbsp Southwest seasoning
• 1/2 cup diced onions
• 1/2 cup diced bell peppers
• 1/4 cup chopped cilantro
• 1 tsp salt
• 1/2 tsp black pepper

Instructions

1. Preheat your oven to 375°F (190°C) and lightly grease a loaf pan.
2. In a large bowl, combine 1.5 lbs ground beef, 1 cup breadcrumbs, 1/4 cup milk, 1 large egg, 1 tbsp Southwest seasoning, 1/2 cup diced onions, 1/2 cup diced bell peppers, 1/4 cup chopped cilantro, 1 tsp salt, and 1/2 tsp black pepper. Mix until just combined; overmixing can make the meatloaf tough.
3. Transfer the mixture to the prepared loaf pan, shaping it into a loaf. Tip: For even cooking, ensure the loaf is uniform in shape.
4. Spread 1/2 cup BBQ sauce evenly over the top of the meatloaf. Tip: Use the back of a spoon for an even layer.
5. Bake in the preheated oven for 50-60 minutes, or until the internal temperature reaches 160°F (71°C). Tip: Let the meatloaf rest for 10 minutes before slicing to retain juices.

Lusciously moist with a smoky-sweet crust, this BBQ Southwest Meatloaf with a Kick is a crowd-pleaser. Serve it sliced with a side of roasted vegetables or atop a toasted bun for a hearty sandwich.

Southwestern Style Turkey Meatloaf

Zesty and satisfying, this Southwestern Style Turkey Meatloaf brings a bold twist to a classic comfort dish. Perfect for beginners, this recipe walks you through each step to ensure a flavorful result every time.

Ingredients

• 1.5 lbs ground turkey
• 1 cup breadcrumbs
• 1 large egg
• 1/2 cup diced onion
• 1/2 cup diced bell pepper
• 1/4 cup chopped cilantro
• 2 tbsp taco seasoning
• 1/2 cup salsa
• 1/4 cup shredded cheddar cheese
• 1 tbsp olive oil

Instructions

1. Preheat your oven to 375°F and lightly grease a loaf pan with olive oil.
2. In a large bowl, combine the ground turkey, breadcrumbs, egg, diced onion, diced bell pepper, chopped cilantro, and taco seasoning until well mixed. Tip: For even distribution, mix the dry ingredients before adding the wet ones.
3. Press the mixture into the prepared loaf pan and top evenly with salsa. Tip: Use the back of a spoon to spread the salsa smoothly over the top.
4. Bake in the preheated oven for 45 minutes, then sprinkle the shredded cheddar cheese on top. Tip: Check the meatloaf’s internal temperature with a thermometer; it should reach 165°F.
5. Return to the oven and bake for an additional 10 minutes, or until the cheese is melted and bubbly.
6. Let the meatloaf rest for 10 minutes before slicing to allow the juices to redistribute.

Unbelievably moist and packed with flavor, this meatloaf pairs wonderfully with a crisp green salad or roasted vegetables. For a fun twist, try serving it in taco shells with extra salsa and avocado slices.

Mexican Inspired Meatloaf with Corn and Peppers

Kickstart your culinary adventure with this Mexican Inspired Meatloaf, a dish that combines the comforting familiarity of meatloaf with the vibrant flavors of Mexico. Perfect for beginners, this recipe guides you through each step to ensure a delicious outcome.

Ingredients

• 1.5 lbs ground beef
• 1 cup breadcrumbs
• 1 cup corn kernels
• 1/2 cup diced green peppers
• 1/2 cup diced red peppers
• 1/4 cup milk
• 2 eggs
• 1 tbsp chili powder
• 1 tsp cumin
• 1 tsp salt
• 1/2 tsp black pepper
• 1/2 cup ketchup
• 1 tbsp brown sugar
• 1 tsp mustard

Instructions

1. Preheat your oven to 350°F (175°C) to ensure it’s ready for baking.
2. In a large bowl, combine 1.5 lbs ground beef, 1 cup breadcrumbs, 1 cup corn kernels, 1/2 cup diced green peppers, 1/2 cup diced red peppers, 1/4 cup milk, 2 eggs, 1 tbsp chili powder, 1 tsp cumin, 1 tsp salt, and 1/2 tsp black pepper. Mix until just combined to avoid overworking the meat.
3. Transfer the mixture to a loaf pan, pressing down gently to form an even layer.
4. In a small bowl, whisk together 1/2 cup ketchup, 1 tbsp brown sugar, and 1 tsp mustard for the glaze.
5. Spread the glaze evenly over the top of the meatloaf.
6. Bake in the preheated oven for 1 hour, or until the internal temperature reaches 160°F (71°C).
7. Let the meatloaf rest for 10 minutes before slicing to allow the juices to redistribute.

Now, this Mexican Inspired Meatloaf boasts a juicy interior with a slightly sweet and tangy glaze, complemented by the crunch of corn and peppers. Serve it alongside a fresh avocado salad or wrapped in warm tortillas for a twist on traditional meatloaf.

Fiery Southwest Meatloaf with Avocado Glaze

Every home cook needs a standout meatloaf recipe, and this Fiery Southwest version with a creamy avocado glaze is sure to impress. Let’s walk through the process together, ensuring even beginners can achieve delicious results.

Ingredients

• 1.5 lbs ground beef
• 1 cup breadcrumbs
• 1 large egg
• 1/2 cup diced onion
• 1/4 cup diced jalapeño
• 2 tbsp Southwest seasoning
• 1/2 cup ketchup
• 1 ripe avocado
• 1/4 cup sour cream
• 1 tbsp lime juice
• 1/2 tsp salt

Instructions

1. Preheat your oven to 375°F and lightly grease a loaf pan.
2. In a large bowl, combine 1.5 lbs ground beef, 1 cup breadcrumbs, 1 large egg, 1/2 cup diced onion, 1/4 cup diced jalapeño, and 2 tbsp Southwest seasoning until evenly mixed. Tip: For even distribution of ingredients, mix with your hands.
3. Press the mixture into the prepared loaf pan, shaping it into a loaf. Tip: Wetting your hands slightly can prevent sticking.
4. Spread 1/2 cup ketchup evenly over the top of the meatloaf.
5. Bake in the preheated oven for 55 minutes, or until the internal temperature reaches 160°F. Tip: Use a meat thermometer for accuracy.
6. While the meatloaf bakes, prepare the avocado glaze by blending 1 ripe avocado, 1/4 cup sour cream, 1 tbsp lime juice, and 1/2 tsp salt until smooth.
7. Let the meatloaf rest for 10 minutes before slicing to allow juices to redistribute.
8. Serve slices topped with the avocado glaze.

Bold flavors and a moist texture make this meatloaf a memorable meal. Try serving it alongside a crisp green salad or roasted vegetables for a complete dinner.

Southwest Meatloaf Muffins with Salsa Topping

Begin your culinary adventure with these Southwest Meatloaf Muffins, a twist on the classic comfort food that’s perfect for any meal. These muffins pack a punch of flavor with a salsa topping, making them a hit for both weeknight dinners and special occasions.

Ingredients

• 1 lb ground beef
• 1/2 cup breadcrumbs
• 1/4 cup milk
• 1 large egg
• 1/2 cup salsa
• 1/4 cup grated cheddar cheese
• 1 tsp chili powder
• 1/2 tsp cumin
• 1/2 tsp salt
• 1/4 tsp black pepper

Instructions

1. Preheat your oven to 375°F (190°C) and lightly grease a muffin tin.
2. In a large bowl, combine 1 lb ground beef, 1/2 cup breadcrumbs, 1/4 cup milk, 1 large egg, 1 tsp chili powder, 1/2 tsp cumin, 1/2 tsp salt, and 1/4 tsp black pepper. Mix until just combined; overmixing can make the meatloaf tough.
3. Divide the mixture evenly among the muffin cups, pressing down slightly to form muffins.
4. Top each muffin with 1 tbsp salsa, spreading it evenly over the top.
5. Bake for 25 minutes, or until the meatloaf muffins reach an internal temperature of 160°F (71°C).
6. Sprinkle 1/4 cup grated cheddar cheese over the muffins and return to the oven for 5 minutes, or until the cheese is melted.
7. Let the muffins cool in the tin for 5 minutes before removing to serve.

Here’s how these muffins turn out: juicy and flavorful with a slightly crispy edge from the muffin tin. The salsa topping adds a tangy kick, while the melted cheese brings it all together. Serve them atop a bed of greens for a lighter meal or alongside roasted vegetables for a hearty dinner.

Cheesy Southwest Meatloaf with Green Chiles

For those who love a twist on classic comfort food, this recipe combines the heartiness of traditional meatloaf with the bold flavors of the Southwest. Follow these steps to create a dish that’s sure to become a new favorite.

Ingredients

• 1.5 lbs ground beef
• 1 cup breadcrumbs
• 1 cup shredded cheddar cheese
• 1/2 cup diced green chiles
• 1/4 cup milk
• 1 large egg
• 1 tbsp Southwest seasoning
• 1/2 tsp salt

Instructions

1. Preheat your oven to 375°F and lightly grease a loaf pan.
2. In a large bowl, combine the ground beef, breadcrumbs, cheddar cheese, green chiles, milk, egg, Southwest seasoning, and salt. Mix until just combined to avoid overworking the meat.
3. Transfer the mixture to the prepared loaf pan, pressing down gently to form an even layer.
4. Bake in the preheated oven for 50 minutes, or until the internal temperature reaches 160°F.
5. Let the meatloaf rest for 10 minutes before slicing to allow the juices to redistribute.

Best enjoyed fresh out of the oven, this Cheesy Southwest Meatloaf with Green Chiles offers a moist texture with a slightly crispy exterior. The melted cheese and green chiles add a delightful burst of flavor in every bite. Serve it alongside a fresh salad or roasted vegetables for a complete meal.

Southwest Meatloaf with Black Beans and Rice

Southwest Meatloaf with Black Beans and Rice combines the hearty comfort of traditional meatloaf with the bold flavors of the Southwest, making it a perfect dish for those looking to spice up their dinner routine.

Ingredients

• 1 lb ground beef
• 1 cup cooked black beans
• 1 cup cooked rice
• 1/2 cup diced onion
• 1/2 cup diced bell pepper
• 1 tbsp Southwest seasoning
• 1/2 cup breadcrumbs
• 1 egg
• 1/4 cup ketchup
• 1 tbsp Worcestershire sauce
• 1/2 tsp salt
• 1/4 tsp black pepper

Instructions

1. Preheat your oven to 375°F (190°C) to ensure it’s ready for baking.
2. In a large mixing bowl, combine the ground beef, black beans, rice, onion, bell pepper, Southwest seasoning, breadcrumbs, egg, ketchup, Worcestershire sauce, salt, and black pepper. Mix until just combined to avoid overworking the meat.
3. Transfer the mixture to a loaf pan, pressing down gently to form an even layer. Tip: For easier removal, line the pan with parchment paper before adding the mixture.
4. Bake in the preheated oven for 50 minutes, or until the internal temperature reaches 160°F (71°C) when checked with a meat thermometer.
5. Let the meatloaf rest for 10 minutes before slicing to allow the juices to redistribute. Tip: This resting period is crucial for a moist meatloaf.
6. Serve slices of the meatloaf with additional cooked rice and black beans on the side for a complete meal. Tip: Garnish with fresh cilantro or a dollop of sour cream for extra flavor.

Vibrant and flavorful, this Southwest Meatloaf with Black Beans and Rice offers a delightful contrast of textures, from the tender meatloaf to the creamy beans and fluffy rice. Consider serving it with a side of avocado slices or a crisp green salad to round out the meal.

Spicy Meatloaf with Southwest Seasonings

Just when you thought meatloaf couldn’t get any better, this Spicy Meatloaf with Southwest Seasonings comes along to prove you wrong. Perfect for those who love a little heat with their comfort food, this dish is a flavorful twist on the classic.

Ingredients

• 1.5 lbs ground beef
• 1 cup breadcrumbs
• 1 large egg
• 1/2 cup milk
• 1/4 cup ketchup
• 2 tbsp Southwest seasoning
• 1 tsp salt
• 1/2 tsp black pepper
• 1/2 cup diced onions
• 1/2 cup diced bell peppers
• 1 tbsp olive oil

Instructions

1. Preheat your oven to 375°F (190°C) and lightly grease a loaf pan with olive oil.
2. In a large bowl, combine the ground beef, breadcrumbs, egg, milk, ketchup, Southwest seasoning, salt, and black pepper. Mix until just combined; overmixing can make the meatloaf tough.
3. Heat the olive oil in a skillet over medium heat. Add the diced onions and bell peppers, sautéing until soft, about 5 minutes. Let cool slightly before adding to the meat mixture.
4. Gently fold the sautéed vegetables into the meat mixture until evenly distributed.
5. Transfer the mixture to the prepared loaf pan, pressing down lightly to remove any air pockets.
6. Bake in the preheated oven for 1 hour, or until the internal temperature reaches 160°F (71°C) when checked with a meat thermometer.
7. Let the meatloaf rest for 10 minutes before slicing to allow the juices to redistribute.

Kick your dinner up a notch with this Spicy Meatloaf, where the Southwest seasonings bring a smoky heat that’s perfectly balanced by the moist, tender texture. Serve it with a side of cool avocado salad to complement the spice.

Southwest Style Meatloaf with Pepper Jack Cheese

Out of all the comfort foods that bring warmth to the table, this Southwest Style Meatloaf with Pepper Jack Cheese stands out for its bold flavors and simple preparation. Perfect for beginners, this recipe walks you through each step to ensure a delicious outcome.

Ingredients

• 1.5 lbs ground beef
• 1 cup breadcrumbs
• 1 large egg
• 1/2 cup milk
• 1/2 cup diced onion
• 1/2 cup diced bell pepper
• 1 tbsp chili powder
• 1 tsp cumin
• 1 tsp garlic powder
• 1/2 tsp salt
• 1/2 tsp black pepper
• 1 cup shredded Pepper Jack cheese
• 1/2 cup ketchup
• 1 tbsp brown sugar
• 1 tsp Worcestershire sauce

Instructions

1. Preheat your oven to 375°F (190°C) and lightly grease a 9×5 inch loaf pan.
2. In a large bowl, combine 1.5 lbs ground beef, 1 cup breadcrumbs, 1 large egg, 1/2 cup milk, 1/2 cup diced onion, 1/2 cup diced bell pepper, 1 tbsp chili powder, 1 tsp cumin, 1 tsp garlic powder, 1/2 tsp salt, and 1/2 tsp black pepper. Mix until just combined; overmixing can make the meatloaf tough.
3. Press half of the meat mixture into the prepared loaf pan. Create a shallow well down the center and fill with 1 cup shredded Pepper Jack cheese. Top with the remaining meat mixture, sealing the edges to encase the cheese.
4. In a small bowl, whisk together 1/2 cup ketchup, 1 tbsp brown sugar, and 1 tsp Worcestershire sauce. Spread this glaze evenly over the top of the meatloaf.
5. Bake in the preheated oven for 55-60 minutes, or until the internal temperature reaches 160°F (71°C). Let it rest for 10 minutes before slicing to allow the juices to redistribute.

Now, this meatloaf boasts a juicy interior with a spicy kick from the Pepper Jack cheese, complemented by the sweet and tangy glaze. Serve it alongside a crisp green salad or roasted vegetables for a complete meal that’s sure to impress.

Zesty Southwest Meatloaf with Cilantro Lime Cream

Gathering around the table for a hearty meal just got more exciting with this zesty twist on a classic comfort dish. Perfect for beginners, this recipe breaks down each step to ensure a flavorful outcome every time.

Ingredients

• 1.5 lbs ground beef
• 1 cup breadcrumbs
• 1 large egg
• 1/2 cup diced onion
• 1/2 cup diced bell pepper
• 2 tbsp Southwest seasoning
• 1/4 cup ketchup
• 1/2 cup sour cream
• 2 tbsp fresh lime juice
• 1/4 cup chopped cilantro
• 1 tsp salt

Instructions

1. Preheat your oven to 375°F (190°C) to ensure it’s ready for baking.
2. In a large mixing bowl, combine 1.5 lbs ground beef, 1 cup breadcrumbs, 1 large egg, 1/2 cup diced onion, 1/2 cup diced bell pepper, 2 tbsp Southwest seasoning, and 1 tsp salt. Mix until just combined to avoid overworking the meat.
3. Transfer the mixture to a loaf pan, shaping it evenly. Tip: For easier removal, line the pan with parchment paper before adding the meatloaf mixture.
4. Spread 1/4 cup ketchup evenly over the top of the meatloaf for a tangy glaze.
5. Bake in the preheated oven for 50 minutes, or until the internal temperature reaches 160°F (71°C). Tip: Use a meat thermometer to check for doneness accurately.
6. While the meatloaf bakes, prepare the cilantro lime cream by whisking together 1/2 cup sour cream, 2 tbsp fresh lime juice, and 1/4 cup chopped cilantro in a small bowl. Tip: Let the cream sit for 10 minutes before serving to allow the flavors to meld.
7. Remove the meatloaf from the oven and let it rest for 10 minutes before slicing. This helps the juices redistribute, ensuring a moist meatloaf.

Unveil a meatloaf that’s moist inside with a slightly crispy exterior, complemented by the fresh, zesty cilantro lime cream. Serve it alongside roasted vegetables or over a bed of greens for a lighter take.

Conclusion

Flavor-packed and full of Southwestern zest, these 12 meatloaf recipes are sure to spice up your dinner routine. Whether you’re craving something smoky, cheesy, or with a kick of heat, there’s a recipe here for every palate. Don’t forget to try your favorites, leave a comment sharing which one you loved most, and pin this article to your Pinterest board for your next culinary adventure!